Quotes of the Day

Antagonist inhibitors such as Dayvigo (lemborexant) and Quviviq (daridorexant) have been approved for treating insomnia, and they appear to be promising. They are, however, quite expensive. One drug that we do find helpful for assisting with sleep is trazodone, a fairly old anti-depressant (approved in 1981) that never really took off. At the doses used to treat depression, 200-300 milligrams per day, it had the unwanted side effect of causing users to fall asleep. That side effect is what we want in a sleep medication, especially if it also improves sleep architecture. We have also had good results with the supplement ashwagandha. [2023] - Peter Attia

Vegetarians and vegans tend to have lower bone mineral density (this translates into elevated fracture risk) compared to meat eaters, not only because they are generally more slender but because of the potential for inadequate vitamin D status and calcium intake. I recommend 2,000 IU of supplemental vitamin D a day for those getting inadequate sun exposure and at least 600 mg of calcium daily via calcium-rich plant foods——preferably low-oxalate dark green leafy vegetables, which include all greens except spinach, chard, and beet greens. (All very healthy foods, but just stingy with their calcium.) [2023] - Michael Greger

Find somebody to love who is a lot like you. There are seven significant similarities: 1. Spiritual harmony. 2. Desire for verbal intimacy and ability to be intimate. 3. Level of energy. 4. Level of ambition. 5. Expectations about roles. 6. Interests. 7. Personal habits (punctuality, cleanliness, orderliness, dependability, responsibility, and weight management). [2002] - Neil Clark Warren

Fully automated trading systems can never beat experienced traders who rely on some level of discretionary trading. [2008] - Yeo Keong Hee

Don't obsess over your sleep, especially if you're having problems. If you need an alarm clock, make sure it's turned away from you so you can't see the numbers. And if you find yourself worrying about poor sleep scores, give yourself a break from your sleep tracker. If you find yourself lying awake in bed, unable to get back to sleep, my advice is to stop fighting it. Get up, go into another room and do something relaxing. Fix a cup of tea (noncaffeinated, obviously), and read a (preferably boring) book until you feel sleepy again. If the sleeplessness persists, the most effective treatment is a form of psychotherapy called Cognitive Behavioral Therapy for Insomnia, or CBT-I. Studies of CBT-I techniques have found that they're more effective than sleeping medications. [2023] - Peter Attia