Quotes of the Day

I think we can reply modest sleep debts as long as they're repaid quickly and in full. A 2016 study by Josiane Broussard showed that 2 nights of makeup sleep (after 4 nights of sleeping 4.5 hours) seemed to return insulin levels and diabetes risk to normal levels. [2017] - W. Chris Winter

In the long run, you save money with a higher deductible, even when factoring in the potential for greater out-of-pocket costs to you when you do have a claim. Insurance should protect you from economic disaster. Don't get carried away with a really high deductible, which can cause financial hardship if you have a claim and lack savings. [2019] - Eric Tyson

While housing construction is a key driver, it tends to lag behind any increased demand for housing due to the significant lead time required to build, especially in larger centers where condominium buildings make up the majority of starts. This lag usually results in an eventual oversupply that persists long after the demand for housing dissipates. Therefore, construction levels tend to peak at the end of the boom phase and through at the middle to end of the slump phase. [2011] - Don R. Campbell

Steer clear of condo complexes that offer units at bargain prices with excessively high monthly maintenance fees. [2013] - Dan S. Barnabic

A polygenic risk score can be inexpensively obtained from a gene chip (array) that assesses over a million common genomic variants that have been quantitatively validated to be associated with risk of a particular cancer, in terms of a score. While these were initially based on European ancestry cohorts, their accuracy and clinical utility have been markedly improved with diverse ancestry and large population data. The principal goal of a polygenic risk score is to identify high-risk individuals so that they can be followed closely. Polygenic risk scores can miss high-risk cases, which is why it's so important to have multiple layers of orthogonal (complementary, additive) data. [2025] - Eric Topol