Quotes of the Day

Poor or inadequate sleep can help tilt us into metabolic dysfunction. Multiple large meta-analyses of sleep studies have revealed a close relationship between sleep duration and risk of type 2 diabetes and the metabolic syndrome. But it cuts both ways: long sleep is also a sign of problems. People who sleep 11 hours or more nightly have a nearly 50% higher risk of all-cause mortality, likely because long sleep = poor quality sleep, but it may also reflect an underlying illness. Similar risk associations have been found between poor or short sleep and hypertension (17%), cardiovascular disease (16%), coronary heart disease (26%), and obesity (38%). [2023] - Peter Attia

You will always love the person most who helps us feel best about ourselves. You want to find someone who shines when you are together. [2002] - Neil Clark Warren

The Galleri test looks at methylation patterns of the cell-free DNA, which are basically chemical changes to the DNA molecules that suggest the presence of cancer. In a study, the Galleri test proved to have a very high specificity, about 99.5%, meaning only 0.5% of tests yielded a false positive. If the test says you have cancer, somewhere in your body, then it's likely that you do. The trade-off is that the resulting sensitivity can be low, depending on the stage. (That is, even if the test says you don't have cancer, you're not necessarily in the clear.) Keep in mind this test still has much higher resolution than radiographic tests such as MRI or mammogram. Those imaging-based tests require "seeing" the tumor, which can happen only when the tumor reaches a certain size. With Galleri, the test is looking at cell-free DNA, which can come from any size tumor-even ones that remain invisible to imaging tests. [2023] - Peter Attia

The Income Tax Act grants to CRA a number of arbitrary powers. The Minister doesn't have to accept your return as filed. In fact, under Section 152(7), CRA has the right to change your tax return if they don't agree with the way you've filed it. They can change your income figures, your deductions or your credits prior to the expiration of a normal "reassessment period," which is 3 years. If you don't agree with how your tax return has been assessed, you have the right to appeal the results. [2020] - Evelyn Jacks

If you feel comfortable with 60-minute charts, you may have a hold time of 3 to 5 days and may want to limit losses to 1 day. If you use a 5-minute time frame, you can have hold times of 45 to 90 minutes while exiting losers after 30 minutes. My typical good day trades last about 90 minutes to 2 hours, and for my longer-term trades I’ll hold for about 3 to 5 days. [2003] - Marcel Link