Quotes of the Day

If you're facing an unfavorable reassessment of tax, know your appeal rights and deadlines. Ask your advisors for information about your rights to voluntarily comply with the law on an informal basis, or in more serious cases, through the court system. Be highly pro-active. [2020] - Evelyn Jacks

During crypto hype, mining equipment such as ASICs becomes incredibly expensive. At the beginning of 2018, for example, they were priced at over $9,000 due to high demand. That’s why you must consider your return on investment before getting yourself involved in mining; sometimes simply buying cryptocurrencies makes more sense than mining them does. The cost of the electricity used by mining computers far exceeds the cost of heating or cooling the house. [2019] - Kiana Danial

Multicancer Early Detection (MCED) assays are constantly getting refined. There are also assays that detect certain proteins or metabolic markers, such as glycosaminoglycans, that indicate a higher likelihood that cancer may be present, as well as blood tests that combine cell-free tumor DNA and proteins in a panel. The test with the most extensive clinical experience to date is known as the GRAIL Galleri. It uses AI to determine whether there is a "cancer signal" and, if present, to help localize its likely organ source. The problem with this test that is marketed for $949 for people aged 50 and older is that the yield is remarkably low. Only 5 per 1,000 people test positive, and, of these, just 2 per 1,000 were actually diagnosed early, in stage 1 or 2, before the cancer spread. The proportion of false negatives among every 1,000 people tested is unknowable. [2025] - Eric Topol

Spend more time with better prospects. Fish for whales, not minnows. [2004] - Brian Tracy

The severity of the slump will depend on the primary factors underpinning it, which typically fall into the following two categories: 1. Overbuilding - due to too much construction. 2. Overpricing - where real estate becomes unaffordable for too many people. Slumps typically initiated by overbuilding are less severe than slumps initiated by overpricing. Slumps led by both overbuilding and overpricing are particularly severe. As a slump phase begins, real estate affordability is adversely affected by tightening credit and prices rising to unrealistic levels. Ironically real estate values continue to increase initially, albeit more slowly than in the preceding boom. Here, rents decrease and vacancy rates increase, clearly at odds with values that continue to rise. [2011] - Don R. Campbell