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When cancers progress in an orderly manner from precancerous stage to small tumor to large tumor to metastasis, screening succeeds. Screening to remove early cancers prevents the development of late cancers, and this saves lives. But if removal of early-stage cancer does not reduce late-stage cancer, screening is unsuccessful, and overdiagnosis becomes a problem. Not every early-stage cancer needs to be destroyed, as many small cancers are contained by the immune system and will never pose a serious health threat. With toxic treatments such as surgery, radiation, and chemotherapy, the treatment may be worse than the disease. [2020] - Jason Fung

Large picture at the top, headline underneath, body copy in two or three columns under the headline, logo and address in the bottom right-hand corner. Setting the headline in big, bold type. The coupon should appear in the lower right-hand corner of the ad. If you want people to respond to your ad by phoning, set the phone number in large type at the end of the body copy. Full-color gets more attention and gives a better impression than black and white. The simpler the layout, the better. Type should be set in black against a clear white background. [2005] - Robert W. Bly

Making a mortgage payment is more or less the same as putting money into your RRSP. In both cases, you're building up the value of an asset and improving your financial security later in life. The combination of mortgage payments (or rent) and retirement savings plus extraordinary, short-term, necessary expenses (like daycare) should equal 30% of your gross pay until you get into your mid-50s. After that, you should be using something like PERC (perc.ecm.lifeworks.com) to provide ongoing guidance as to how much you should be saving. [2021] - Frederick Vettese

Usually, only about five to seven skills, or key result areas, determine most of the success in any field of endeavor. Your first job is to identify these key skills and write them down. [2004] - Brian Tracy

The secret of success is making your vocation your vacation. [1989] - Anthony Robbins