Quotes of the Day

You will probably want to ask questions one and two out loud. You will observe quietly the answer to question three. You will be prepared to make the case for questions four and five, when the appropriate time in the interview arises. [2013] - Richard N. Bolles

The term cancer chemoprevention was introduced by the NIH in 1976 to denote foods, supplements, or drugs that may block progression of cancer. One of the most promising chemopreventive drugs is the old diabetes drug metformin. Studies have demonstrated that in type 2 diabetics, metformin may potentially reduce the risk of cancer by as much as 21 percent to 57 percent. Specifically, long-term metformin use in women with type 2 diabetes was associated with a more than 50 percent reduction in breast cancer risk. Metformin works by reducing glucose to the growing cancer without the pro-growth effects of the insulin/IGF-1/PI3K pathway. It also activates AMPK, an important nutrient sensor and growth pathway, which rapidly inhibits cellular protein synthesis and growth. Some research has indicated that this beneficial anticancer effect might extend to nondiabetics as well. [2020] - Jason Fung

For older people especially, and almost definitely for those with no heirs, an annuity - either fixed or variable - can make enormous sense. With an annuity, you give up your principal, and in return you enjoy a yield typically far greater than you would likely get with any other fixed-income option. Many horrible annuities are out there. Most of the really bad ones are variable annuities. If you are interested in an annuity, contact the different insurance companies. It's a good idea to compare rates of return and product offerings. For more information on annuities, visit the Canadian Life and Health Insurance Association website at www.clhia.ca. [2013] - Russell Wild

Date-scheduling System: 1. Give someone two date options from your calendar. 2. If you have multiple matches that are ready to meet up, ask one, and then wait twenty-four hours before asking our another. 3. If you haven't heard back within twenty-four hours, go ahead and message your next date, but don't give specific times. 4. If you have more than two dates to schedule at once, stay vague with your availability, and email them at the same time so you have room to plan. [2013] - Laurie Davis

A standard rule for determining where to invest rules out properties located more than four hours' driving distance of where you live. This ensures you can easily reach the property in a timely fashion if required. [2020] - Douglas Gray